Cancer Screening: Client Reminders — Colorectal Cancer

Findings and Recommendations


The Community Preventive Services Task Force (CPSTF) recommends the use of client reminders to increase screening for colorectal cancers on the basis of strong evidence of effectiveness.

The full CPSTF Finding and Rationale Statement and supporting documents for Increasing Cancer Screening: Client Reminders [for Breast, Cervical, and Colorectal Cancers] are available in The Community Guide Collection on CDC Stacks.

Intervention


Client reminders are written (letter, postcard, email) or telephone messages (including automated messages) advising people that they are due for screening. Client reminders may be enhanced by one or more of the following:

  • Follow-up printed or telephone reminders
  • Additional text or discussion with information about indications for, benefits of, and ways to overcome barriers to screening
  • Assistance in scheduling appointments

These interventions can be untailored to address the overall target population or tailored with the intent to reach one specific person, based on characteristics unique to that person, related to the outcome of interest, and derived from an individual assessment.

About The Systematic Review


The CPSTF finding for client reminders to increase screening for colorectal cancer by FOBT is based on evidence from a Community Guide systematic review published in 2008 (Baron et al., 4 studies, search period 1966-2004) combined with more recent evidence (3 studies, search period 2004-2008). The finding for colorectal cancer screening by colonoscopy or flexible sigmoidoscopy is based on evidence from a Community Guide systematic review published in 2008 (Baron et al., 0 studies, search period 1966-2004) combined with more recent evidence (2 studies, search period 2004-2008).

The systematic reviews were conducted on behalf of the CPSTF by a team of specialists in systematic review methods, and in research, practice, and policy related to cancer prevention and control.

Study Characteristics


Following are characteristics of included FOBT studies from the updated search period.

  • Interventions used print reminders. None were tailored and two were enhanced.
  • Reminders were delivered by clinical practices or organizations, or screening programs.
  • Outcomes were assessed by survey and medical record review.
  • Where specified, interventions were conducted in the U.S. and Italy.
  • One study reported including nonwhite participants, although it did not provide more specific information, and two studies reported including mixed urban/rural or non-urban populations.

The two included studies that evaluated client reminders to increase screening by flexible sigmoidoscopy, colonoscopy, or barium enema provided information about incremental effects of client reminders on use of screening methods.

Summary of Results


Results from the 2008 Review

The original colorectal cancer review included 4 studies on client reminders to increase cancer screening by FOBT.

Results from the Updated Review

The updated review included 3 additional studies on colorectal cancer screening by FOBT. Combined evidence from both the original and the updated review showed the following.

  • When added to other types of interventions, the median incremental effect for FOBT use was an increase of 10.9 percentage points (5 studies with 9 study arms)

Two studies with five study arms that evaluated client reminders to increase colorectal cancer by flexible sigmoidoscopy, colonoscopy, or barium enema showed a low estimated effect.

Summary of Economic Evidence


The updated search for evidence included five studies about client reminders to increase screening for breast cancer (1 study) or colorectal cancer (4 studies). One study provided only cost information and four provided cost-effectiveness information.

Applicability


Tailored and untailored client reminder interventions to increase colorectal cancer screening by FOBT should be applicable across a range of settings and populations, provided they are adapted and targeted for a specific population and delivery context.

Evidence Gaps


The CPSTF identified several areas that have limited information. Additional research and evaluation could help answer the following questions and fill remaining gaps in the evidence base. (What are evidence gaps?)

The following outlines evidence gaps for client reminders to increase breast, cervical, or colorectal cancer screening.

  • How do newer methods of communication (e.g., the Internet, e-mail, text messages, or automated telephone calls) influence the effectiveness of client reminder interventions?
  • To what extent does effectiveness vary for groups overdue for screening or never screened?
  • Does effectiveness vary according to the source of client reminders (e.g., clinic or practice versus screening registry or program)?
  • Do reminders for screenings for multiple cancer sites work as well as those for a single cancer site?
  • Are interventions effective for promoting colorectal cancer screening with methods other than FOBT?
  • Are interventions to promote colorectal cancer screening equally effective when addressing colorectal cancer screening more generally, as when specific to one type of test?
  • What are the incremental effects of adding intervention components to other interventions?
  • What is the influence of health system factors on intervention effectiveness?

Implementation Considerations and Resources


  • Basic infrastructure, staffing, and computer support is needed to identify patients due for screening and deliver reminders efficiently.
  • Funds may be required to generate and deliver reminders, though programs implemented on a large scale may cost little per person.

Crosswalks

Healthy People 2030 icon Healthy People 2030 includes the following objective related to this CPSTF recommendation.